In FY 2025, the Transformative Research in the Education Sciences Grants Program aims to drive significant advancements in education by combining evidence-based principles from the learning sciences with cutting-edge technology. The program seeks to accelerate learning and address longstanding educational inequities through innovative research projects characterized by bold, interdisciplinary approaches and the potential for high-impact outcomes. Emphasizing scalability and rigorous evaluation, funded projects will navigate risks associated with implementation challenges by fostering ongoing reassessment and adaptation to achieve their ambitious goals.